Skip to content



Nichols AL, Noridomi K, Hughes CR, Jalali-Yazdi F, Eaton JB, Lai LH, Advani G, Lukas RJ, Lester HA, Chem L, Roberts RW. α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor. (2018), ACS Chem. Biol., 132568–2576. doi10.1021/acschembio.8b00513  [PDF]


Cetin M, Gross GG, Evenson WE, Jalali-Yazdi F, Takahashi TT, Arnold D, Roberts RW. RasIns: Genetically Encoded Intrabodies of Activated Ras Proteins. (2017), J. Mol. Biol., 429, 562. doi: 10.1016/j.jmb.2016.11.008 [PDF]


Jalali-Yazdi, F., Lai L.H.., Takahashi, T.T., Roberts, R.W., 2016. High-Throughput Measurement of Binding Kinetics by mRNA Display and Next-Generation Sequencing. Angewandte Chemie 128, 4075-4078. doi: 10.1002/anie.201600077 [PDF]


Jalali-Yazdi, F., Takahashi, T.T., Roberts, R.W., 2015. General, Label-Free Method for Determining Kd and Ligand Concentration Simultaneously. Analytical Chemistry 87, 11755-11762. doi:10.1021/acs.analchem.5b03069. doi: 10.1021/acs.analchem.5b03069 [PDF]


Jalali-Yazdi, F., Corbin, J.M., Takahashi, T.T., Roberts, R.W., 2014. Robust, Quantitative Analysis of Proteins using Peptide Immunoreagents, in Vitro Translation, and an Ultrasensitive Acoustic Resonant Sensor. Analytical Chemistry 86, 4715-4722. doi: 10.1021/ac500084d [PDF]

Howell, S.M., Fiacco, S.V., Takahashi, T.T., Jalali-Yazdi, F., Millward, S.W., Hu, B., Wang, P., Roberts, R.W., 2014. Serum Stable Natural Peptides Designed by mRNA Display. Scientific Reports 4. doi: 10.1038/srep06008 [PDF]


Xiao, L., Hung, K.-C., Takahashi, T.T., Joo, K.-I., Lim, M., Roberts, R.W., Wang, P., 2013. Antibody-Mimetic Ligand Selected by mRNA Display Targets DC-SIGN for Dendritic Cell-Directed Antigen Delivery. ACS chemical biology 8, 967-977. doi: 10.1021/cb300680c [PDF]

Mora, R.J., Roberts, R.W., Arnold, D.B., 2013. Recombinant Probes Reveal Dynamic Localization of CaMKII alpha within Somata of Cortical Neurons. Journal of Neuroscience 33, 14579-14590. doi: 10.1523/JNEUROSCI.2108-13.2013.  [PDF]

Gross, G.G., Junge, J.A., Mora, R.J., Kwon, H.-B., Olson, C.A., Takahashi, T.T., Liman, E.R., Ellis-Davies, G.C.R., McGee, A.W., Sabatini, B.L., Roberts, R.W., Arnold, D.B., 2013. Recombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons. Neuron 78, 971-985. doi:10.1016/j.neuron.2013.04.017 [PDF]


Olson, C.A., Nie, J., Diep, J., Al-Shyoukh, I., Takahashi, T.T., Al-Mawsawi, L.Q., Bolin, J.M., Elwell, A.L., Swanson, S., Stewart, R., Thomson, J.A., Soh, H.T., Roberts, R.W., Sun, R., 2012. Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display. Angewandte Chemie-International Edition 51, 12449-12453. doi: 10.1002/anie.201207005 [PDF]


Olson, C.A., Adams, J.D., Takahashi, T.T., Qi, H., Howell, S.M., Wu, T.-T., Roberts, R.W., Sun, R., Soh, H.T., 2011. Rapid mRNA-Display Selection of an IL-6 Inhibitor Using Continuous-Flow Magnetic Separation. Angewandte Chemie-International Edition 50, 8295-8298. doi: 10.1002/anie.201101149 [PDF]


Qi, X., Xia, T., Roberts, R.W., 2010. Acridine-N Peptide Conjugates Display Enhanced Affinity and Specificity for boxB RNA Targets. Biochemistry 49, 5782-5789. doi: 10.1021/bi100634h [PDF]

Ishikawa, F.N., Curreli, M., Olson, C.A., Liao, H.-I., Sun, R., Roberts, R.W., Cote, R.J., Thompson, M.E., Zhou, C., 2010. Importance of Controlling Nanotube Density for Highly Sensitive and Reliable Biosensors Functional in Physiological Conditions. Acs Nano 4, 6914-6922. doi: 10.1021/nn101198u [PDF]


Liao, H.-I., Olson, C.A., Hwang, S., Deng, H., Wong, E., Baric, R.S., Roberts, R.W., Sun, R., 2009. mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein. Journal of Biological Chemistry 284, 17512-17520. doi: 10.1074/jbc.M901547200 [PDF]

Ja, W.W., Carvalho, G.B., Madrigal, M., Roberts, R.W., Benzer, S., 2009. The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides. Protein Science 18, 2203-2208. doi: 10.1002/pro.221 [PDF]

Ishikawa, F.N., Chang, H.-K., Curreli, M., Liao, H.-I., Olson, C.A., Chen, P.-C., Zhang, R., Roberts, R.W., Sun, R., Cote, R.J., Thompson, M.E., Zhou, C., 2009. Label-Free, Electrical Detection of the SARS Virus N-Protein with Nanowire Biosensors Utilizing Antibody Mimics as Capture Probes. Acs Nano 3, 1219-1224. doi: 10.1021/nn900086c [PDF]


Olson, C.A., Liao, H.-I., Sun, R., Roberts, R.W., 2008. mRNA display selection of a high-affinity, modification-specific phospho-I kappa B alpha-binding fibronectin. ACS chemical biology 3, 480-485. doi: 10.1021/cb800069c [PDF]

Fiacco, S.V., Roberts, R.W., 2008. N-Methyl Scanning Mutagenesis Generates Protease-Resistant G Protein Ligands with Improved Affinity and Selectivity. Chembiochem : a European journal of chemical biology 9, 2200-2203. doi: 10.1002/cbic.200800208 [PDF]

Austin, R.J., Ja, W.W., Roberts, R.W., 2008. Evolution of class-specific peptides targeting a hot spot of the G alpha s subunit. Journal of Molecular Biology 377, 1406-1418. doi: 10.1016/j.jmb.2008.01.032 [PDF]


Olson, C.A., Roberts, R.W., 2007. Design, expression, and stability of a diverse protein library based on the human fibronectin type III domain. Protein Science 16, 476-484. doi: 10.1110/ps.062498407 [PDF]

Millward, S.W., Fiacco, S., Austin, R.J., Roberts, R.W., 2007. Design of cyclic peptides that bind protein surfaces with antibody-like affinity. ACS chemical biology 2, 625-634. doi: 10.1021/cb7001126 [PDF]

Ja, W.W., West, A.P., Jr., Delker, S.L., Bjorkman, P.J., Benzer, S., Roberts, R.W., 2007. Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. Nature Chemical Biology 3, 415-419. doi: 10.1038/nchembio.2007.2 [PDF]


Ja, W.W., Wiser, O., Austin, R.J., Jan, L.Y., Roberts, R.W., 2006. Turning G proteins on and off using peptide ligands. ACS chemical biology 1, 570-574. doi: 10.1021/cb600345k [PDF]