2022
Grindel BJ, Engel BJ, Ong JN, Srinivasamani A, Liang X, Zacharias NM, Bast RC, Curran MA, Takahashi TT, Roberts RW, Millward SW. (2022). Directed Evolution of PD-L1-Targeted Affibodies by mRNA Display. ACS Chem. Biol., 17(6), 1543-1555. doi: 10.1021/acschembio.2c00218
Lin WZS, Evenson WE, Bostic WKV, Roberts RW, Malmstadt N. (2022). Compatibility of popular three-dimensional printed microfluidics materials with in vitro enzymatic reactions. ACS Appl. Bio Mater., 5(2), 818-824. doi: 10.1021/acsabm.1c01180
2021
Kamalinia G, Grindel BJ, Takahashi TT, Millward SW, Roberts RW. (2021). Directing evolution of novel ligands by mRNA display. Chem. Soc. Rev., 50(16), 9055-9103. doi: 10.1039/D1CS00160D
2020
Evenson WE, Lin WZS, Pang K, Czaja A, Jalali-Yazdi F, Takahashi TT, Malmstadt N, Roberts RW. (2020). Enabling Flow-Based Kinetic Off-Rate Selections Using a Microfluidic Enrichment Device. Anal. Chem., 92(15), 10218-10222. doi: 10.1021/acs.analchem.0c01867.
Kamalinia G, Engel BJ, Srinivasamani A, Grindel BJ, Ong JN, Curran MA, Takahashi TT, Millward SW, Roberts RW. (2020). mRNA display discovery of a novel programmed death ligand 1 (PD-L1) binding peptide (a peptide ligand for PD-L1). ACS Chem. Biol., 15(6), 1630-1641. doi: 10.1021/acschembio.0c00264.
Lin WZS, Evenson WE, Pang K, Roberts RW, Malmstadt N. (2020). Preparation of Peptides with High Affinity to Cancer Targets in mRNA Display via Continuous-Flow Microfluidics. Biophys. J., 118(3), 152a.
2019
Ludwicki MB, Li J, Stephens EA, Roberts RW, Koise S, Hammon PT, DeLisa MP. (2019). Broad-spectrum proteome editing with an engineered bacterial ubiquitin ligase mimic. ACS Cent. Sci., 5(5), 852-866. doi: 10.1021/acscentsci.9b00127
2018
Nichols AL, Noridomi K, Hughes CR, Jalali-Yazdi F, Eaton JB, Lai LH, Advani G, Lukas RJ, Lester HA, Chem L, Roberts RW. (2018). α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor. ACS Chem. Biol., 13, 2568–2576. doi: 10.1021/acschembio.8b00513
2017
Cetin M, Gross GG, Evenson WE, Jalali-Yazdi F, Takahashi TT, Arnold D, Roberts RW. (2017). RasIns: Genetically Encoded Intrabodies of Activated Ras Proteins. J. Mol. Biol., 429, 562. doi: 10.1016/j.jmb.2016.11.008
2016
Jalali-Yazdi, F., Lai L.H.., Takahashi, T.T., Roberts, R.W. (2016). High-Throughput Measurement of Binding Kinetics by mRNA Display and Next-Generation Sequencing. Angewandte Chemie International Edition, 55(12), 4007-4010. doi: 10.1002/anie.201600077
2015
Jalali-Yazdi, F., Takahashi, T.T., Roberts, R.W. (2015). General, Label-Free Method for Determining Kd and Ligand Concentration Simultaneously. Analytical Chemistry, 87(23), 11755-11762. doi: 10.1021/acs.analchem.5b03069
2014
Jalali-Yazdi, F., Corbin, J.M., Takahashi, T.T., Roberts, R.W. (2014). Robust, Quantitative Analysis of Proteins using Peptide Immunoreagents, in Vitro Translation, and an Ultrasensitive Acoustic Resonant Sensor. Analytical Chemistry, 86(10), 4715-4722. doi: 10.1021/ac500084d
Howell, S.M., Fiacco, S.V., Takahashi, T.T., Jalali-Yazdi, F., Millward, S.W., Hu, B., Wang, P., Roberts, R.W. (2014). Serum Stable Natural Peptides Designed by mRNA Display. Scientific Reports, 4(1), 6008.doi: 10.1038/srep06008
2013
Xiao, L., Hung, K.-C., Takahashi, T.T., Joo, K.-I., Lim, M., Roberts, R.W., Wang, P. (2013). Antibody-Mimetic Ligand Selected by mRNA Display Targets DC-SIGN for Dendritic Cell-Directed Antigen Delivery. ACS Chem. Bio., 8(5), 967-977. doi: 10.1021/cb300680c
Mora, R.J., Roberts, R.W., Arnold, D.B. (2013). Recombinant Probes Reveal Dynamic Localization of CaMKII alpha within Somata of Cortical Neurons. Journal of Neuroscience 33(36), 14579-14590. doi: 10.1523/JNEUROSCI.2108-13.2013
Gross, G.G., Junge, J.A., Mora, R.J., Kwon, H.-B., Olson, C.A., Takahashi, T.T., Liman, E.R., Ellis-Davies, G.C.R., McGee, A.W., Sabatini, B.L., Roberts, R.W., Arnold, D.B. (2013). Recombinant Probes for Visualizing Endogenous Synaptic Proteins in Living Neurons. Neuron, 78(6), 971-985. doi: 10.1016/j.neuron.2013.04.017
2012
Olson, C.A., Nie, J., Diep, J., Al-Shyoukh, I., Takahashi, T.T., Al-Mawsawi, L.Q., Bolin, J.M., Elwell, A.L., Swanson, S., Stewart, R., Thomson, J.A., Soh, H.T., Roberts, R.W., Sun, R. (2012). Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display. Angewandte Chemie-International Edition, 51(50), 12449-12453. doi: 10.1002/anie.201207005
2011
Olson, C.A., Adams, J.D., Takahashi, T.T., Qi, H., Howell, S.M., Wu, T.-T., Roberts, R.W., Sun, R., Soh, H.T. (2011). Rapid mRNA-Display Selection of an IL-6 Inhibitor Using Continuous-Flow Magnetic Separation. Angewandte Chemie-International Edition, 50(36), 8295-8298. doi: 10.1002/anie.201101149
2010
Qi, X., Xia, T., Roberts, R.W. (2010). Acridine-N Peptide Conjugates Display Enhanced Affinity and Specificity for boxB RNA Targets. Biochemistry, 49, 5782-5789. doi: 10.1021/bi100634h
Ishikawa, F.N., Curreli, M., Olson, C.A., Liao, H.-I., Sun, R., Roberts, R.W., Cote, R.J., Thompson, M.E., Zhou, C. (2010). Importance of Controlling Nanotube Density for Highly Sensitive and Reliable Biosensors Functional in Physiological Conditions. ACS Nano, 4(11), 6914-6922. doi: 10.1021/nn101198u
2009
Liao, H.-I., Olson, C.A., Hwang, S., Deng, H., Wong, E., Baric, R.S., Roberts, R.W., Sun, R. (2009). mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein. Journal of Biological Chemistry, 284(26), 17512-17520. doi: 10.1074/jbc.M901547200
Ja, W.W., Carvalho, G.B., Madrigal, M., Roberts, R.W., Benzer, S. (2009). The Drosophila G protein-coupled receptor, Methuselah, exhibits a promiscuous response to peptides. Protein Science, 18(11), 2203-2208. doi: 10.1002/pro.221
Ishikawa, F.N., Chang, H.-K., Curreli, M., Liao, H.-I., Olson, C.A., Chen, P.-C., Zhang, R., Roberts, R.W., Sun, R., Cote, R.J., Thompson, M.E., Zhou, C. (2009). Label-Free, Electrical Detection of the SARS Virus N-Protein with Nanowire Biosensors Utilizing Antibody Mimics as Capture Probes. ACS Nano, 3(5), 1219-1224. doi: 10.1021/nn900086c
2008
Olson, C.A., Liao, H.-I., Sun, R., Roberts, R.W. (2008). mRNA display selection of a high-affinity, modification-specific phospho-I kappa B alpha-binding fibronectin. ACS Chem. Bio., 3(8), 480-485. doi: 10.1021/cb800069c
Fiacco, S.V., Roberts, R.W. (2008). N-Methyl Scanning Mutagenesis Generates Protease-Resistant G Protein Ligands with Improved Affinity and Selectivity. ChemBioChem: a European Journal of Chemical Biology, 9(14), 2200-2203. doi: 10.1002/cbic.200800208
Austin, R.J., Ja, W.W., Roberts, R.W. (2008). Evolution of class-specific peptides targeting a hot spot of the G alpha s subunit. Journal of Molecular Biology, 377(5), 1406-1418. doi: 10.1016/j.jmb.2008.01.032
2007
Olson, C.A., Roberts, R.W. (2007). Design, expression, and stability of a diverse protein library based on the human fibronectin type III domain. Protein Science, 16(3), 476-484. doi: 10.1110/ps.062498407
Millward, S.W., Fiacco, S., Austin, R.J., Roberts, R.W. (2007). Design of cyclic peptides that bind protein surfaces with antibody-like affinity. ACS Chem. Bio., 2(9), 625-634. doi: 10.1021/cb7001126
Ja, W.W., West, A.P., Jr., Delker, S.L., Bjorkman, P.J., Benzer, S., Roberts, R.W. (2007). Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. Nature Chemical Biology, 3, 415-419. doi: 10.1038/nchembio.2007.2
2006
Ja, W.W., Wiser, O., Austin, R.J., Jan, L.Y., Roberts, R.W. (2006). Turning G proteins on and off using peptide ligands. ACS Chem. Bio., 1(9), 570-574. doi: 10.1021/cb600345k